Three-dimensional printing of a sucrose scaffold based on pneumatic control: relevant technological parameters

doi:10.3969/j.issn.2095-4344.2016.25.020

Abstract

Abstract:

BACKGROUND: The sucrose is an ideal material for auxiliary support and mold filling that is suitable for application in the medical field with three-dimensional (3D) printing. In China, there are many studies about the 3D printing with sucrose, but the accuracy and porosity of the stent are still unclear.
OBJECTIVE: To explore the technological parameters of the sucrose scaffold by 3D printing technology.
METHODS: From the perspective of physical and chemical properties, the sucrose viscosity and thermal decomposition with the change of temperature were analyzed. Based on the pneumatic controlled FDM technology, the mature sucrose scaffold was obtained by researching the match of temperature and pressure, layer setting, as well as the match of speed and pressure. Then the scaffold was demarcated with microscope, and the porosity was measured by immersion in absolute ethyl alcohol.
RESULTS AND CONCLUSION: The sucrose was completely melted at 180 oC, with the biggest liquidity. When the temperature was over 195 oC, the caramel reaction occurred. As the temperature increased, the sucrose viscosity decreased. The optimal molding parameters of the sucrose scaffold with pneumatic control-based 3D printing were 170 oC-0.2 MPa-12 mm/s (temperature-pressure-printing speed). The line width and mean porosity of the well-shaped sucrose scaffold were 700 μm and 81.893%, respectively.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Sucrose, Air Pressure, Stents, Tissue Engineering

CLC Number:

R318

Zhao Xiao-bo, Sun Kai-yu, Liu Chong . Three-dimensional printing of a sucrose scaffold based on pneumatic control: relevant technological parameters[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(25): 3778-3784.

Figures/Tables 7

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